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Flights from Chicago to San Francisco

Nonstop options and typical one-way fares by airline.

Typical fares by airline

AirlineRouteTypical one-way fare*
American AirlinesORD → SFO$204.92
Southwest AirlinesMDW → SFO$222.27
United AirlinesORD → SFO$284.16

*Historical average incl. taxes and fees (2025 Q2 (Apr-Jun 2025)); not a live quote.

Frequently asked questions

Which airlines fly nonstop from Chicago to San Francisco?+

American Airlines, Southwest Airlines, United Airlines.

What is the lowest typical fare?+

The lowest historical average one-way fare in our data is $204.92 on American Airlines (2025 Q2 (Apr-Jun 2025)). Actual fares vary.

Can an agent book this for me?+

Yes, call +1-800-000-0000.